In 2023, David got in touch with us to tell us the story of his wife, Barbara.
Barbara was diagnosed with cancer, but after a bout of pneumonia that caused her primary and secondary tumours to grow and weaken her immune system, she agreed with her oncologists not to proceed with any formal treatment.
Coincidentally, her Marodyne LiV was delivered around the same time to help with her osteoporosis, and Barbara started using it daily to help improve her quality of life.
Barbara has continued to use her device every day, and the results are encouraging. This is what David had to say: “Here we are 10 months later and a recent CT scan shows that both Barbara’s primary lung cancer and secondary adrenal cancer are quiescent, with no secondary hot spots, to the extent that her doctor was prepared to say that she is in remission!”.
David was fascinated to watch Professor Rubin’s video on Low-intensity Vibration therapy. His work with T-cells (immune cells that develop from stem cells in bone marrow) made David wonder if his wife’s use of her Marodyne LiV has contributed to her cancer going into remission.
In 2023, David got in touch with us to tell us the story of his wife, Barbara.
Barbara was diagnosed with cancer, but after a bout of pneumonia that caused her primary and secondary tumours to grow and weaken her immune system, she agreed with her oncologists not to proceed with any formal treatment.
Coincidentally, her Marodyne LiV was delivered around the same time to help with her osteoporosis, and Barbara started using it daily to help improve her quality of life.
Barbara has continued to use her device every day, and the results are encouraging. This is what David had to say: “Here we are 10 months later and a recent CT scan shows that both Barbara’s primary lung cancer and secondary adrenal cancer are quiescent, with no secondary hot spots, to the extent that her doctor was prepared to say that she is in remission!”.
David was fascinated to watch Professor Rubin’s video on Low-intensity Vibration therapy. His work with T-cells (immune cells that develop from stem cells in bone marrow) made David wonder if his wife’s use of her Marodyne LiV has contributed to her cancer going into remission.
David got in contact with Professor Rubin, the inventor of the Marodyne LiV, to share his wife’s story. Here is his response:
“Our group is very interested in seeing LiV used in conjunction with standard therapies for cancer, but primarily for protection of the musculoskeletal system during treatment of the disease.”
“To demonstrate that the LiV signal is safe for those battling cancer, we have done several studies that show: the LiV signal does not promote cancer susceptibility and protects bone quality/quantity without fueling advancement of cancer.”
“T-cells are critical to fight any disease and are particularly important in slowing cancer advancement. We have shown in vitro that the LiV signal can effectively stimulate T-cell proliferation and suppress exhaustion, making T-cells more active.”
“The bottom line is that mechanical signals are critical to keep not only the musculoskeletal system healthy, but to keep the immune system working as well as it can. We remain hopeful that the LiV signal will prove a useful part of cancer therapies, and that its influence can extend beyond bone and muscle, to perhaps help the immune system or slow tumour growth.”
“While I find the summary of your wife’s status very interesting (and hopeful), I would not want you or anyone else thinking that LiV is a treatment for cancer. We have a long way to go, but outcomes that are evident from your wife and others are really encouraging to us, and we promise to keep moving forward.”
David got in contact with Professor Rubin, the inventor of the Marodyne LiV, to share his wife’s story. Here is his response:
“Our group is very interested in seeing LiV used in conjunction with standard therapies for cancer, but primarily for protection of the musculoskeletal system during treatment of the disease.”
“To demonstrate that the LiV signal is safe for those battling cancer, we have done several studies that show: the LiV signal does not promote cancer susceptibility and protects bone quality/quantity without fueling advancement of cancer.”
“T-cells are critical to fight any disease and are particularly important in slowing cancer advancement. We have shown in vitro that the LiV signal can effectively stimulate T-cell proliferation and suppress exhaustion, making T-cells more active.”
“The bottom line is that mechanical signals are critical to keep not only the musculoskeletal system healthy, but to keep the immune system working as well as it can. We remain hopeful that the LiV signal will prove a useful part of cancer therapies, and that its influence can extend beyond bone and muscle, to perhaps help the immune system or slow tumour growth.”
“While I find the summary of your wife’s status very interesting (and hopeful), I would not want you or anyone else thinking that LiV is a treatment for cancer. We have a long way to go, but outcomes that are evident from your wife and others are really encouraging to us, and we promise to keep moving forward.”
YouTube video: T-Cell Therapy, Stony Brook Professor Rubin
In a video from The State University of New York, inventor of the Marodyne LiV device, Professor Clinton Rubin, explains his work on using Low-intensity Vibration to accelerate T-cell proliferation, which could potentially have an impact on cancer therapeutics. Watch the full video here.
Xiong X, et al. (2024) Enhancing anti-tumour potential: low-intensity vibration suppresses osteosarcoma progression and augments MSCs’ tumour-suppressive abilities, Theranostics, 14(4):1430-1449.
Researchers set out to investigate new treatment strategies for osteosarcoma, a common malignant bone tumour. They found that Low-intensity Vibration promoted the conversion of cells within bone marrow into tumour-suppressing cells. Read the full paper here.
Pagnotti GM, Chan ME, Adler BJ, Shroyer KR, Rubin J, Bain SD, Rubin CT. (2016) Low intensity vibration mitigates tumour progression and protects bone quantity and quality in a murine model of myeloma, Bone, 90:69-79.
Myeloma is a type of blood cancer that develops from plasma cells, and facilitates the destruction of bone and marrow. In this study, researchers set out to evaluate whether Low-intensity Vibration could protect bone during myeloma progression, finding that it not only slowed myeloma associated decline in bone quality but also inhibited tumour progression. Read the full paper here.
Youtube video: Low Intensity Vibration Therapy: New Hope For Cancer & Bone Health?
In this video from physical therapist Margaret Martin, she discusses Low-intensity Vibration therapy and the potential for it’s role in cancer therapeutics with leading researchers Theresa Guise and Gabe Pagnotti. Watch the full video here.
Yi, X, Wright, L.E, Pagnotti, G.M. et al. (2020) Mechanical suppression of breast cancer cell invasion and paracrine signalling to osteoclasts requires nucleo-cytoskeletal connectivity. Bone Res 8, 40.
In this 2020 study, researchers examined the mechanisms through which human breast cancer cells respond to Low-intensity Vibration. The data they gathered showed that Low-intensity Vibration reduces the metastatic potential of the cancer cells, slowing their spread. Read the full paper here.
YouTube video: T-Cell Therapy, Stony Brook Professor Rubin
In a video from The State University of New York, inventor of the Marodyne LiV device, Professor Clinton Rubin, explains his work on using Low-intensity Vibration to accelerate T-cell proliferation, which could potentially have an impact on cancer therapeutics. Watch the full video here.
Xiong X, et al. (2024) Enhancing anti-tumour potential: low-intensity vibration suppresses osteosarcoma progression and augments MSCs’ tumour-suppressive abilities, Theranostics, 14(4):1430-1449.
Researchers set out to investigate new treatment strategies for osteosarcoma, a common malignant bone tumour. They found that Low-intensity Vibration promoted the conversion of cells within bone marrow into tumour-suppressing cells. Read the full paper here.
Pagnotti GM, Chan ME, Adler BJ, Shroyer KR, Rubin J, Bain SD, Rubin CT. (2016) Low intensity vibration mitigates tumour progression and protects bone quantity and quality in a murine model of myeloma, Bone, 90:69-79.
Myeloma is a type of blood cancer that develops from plasma cells, and facilitates the destruction of bone and marrow. In this study, researchers set out to evaluate whether Low-intensity Vibration could protect bone during myeloma progression, finding that it not only slowed myeloma associated decline in bone quality but also inhibited tumour progression. Read the full paper here.
Youtube video: Low Intensity Vibration Therapy: New Hope For Cancer & Bone Health?
In this video from physical therapist Margaret Martin, she discusses Low-intensity Vibration therapy and the potential for it’s role in cancer therapeutics with leading researchers Theresa Guise and Gabe Pagnotti. Watch the full video here.
Yi, X, Wright, L.E, Pagnotti, G.M. et al. (2020) Mechanical suppression of breast cancer cell invasion and paracrine signalling to osteoclasts requires nucleo-cytoskeletal connectivity. Bone Res 8, 40.
In this 2020 study, researchers examined the mechanisms through which human breast cancer cells respond to Low-intensity Vibration. The data they gathered showed that Low-intensity Vibration reduces the metastatic potential of the cancer cells, slowing their spread. Read the full paper here.
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